The Beans or Brain?- The ACORN trial and effects of cefepime and pip-tazo on neuro and renal outcomes

In the Emergency Department, we often have to initiate empiric antibiotic treatment for sick, undifferentiated patients.  Cefepime and Piperacillin-Tazobactam (pip-tazo) are common antibiotic options for coverage of gram-negative organisms, such as pseudomonas. But is one better than the other?

In this podcast, we will critically appraise The ACORN Trial- an article that examines the risks of acute kidney injury and/or neurologic dysfunction in patients treated empirically with one of these antibiotics. 

 

 

Click HERE for our detailed shownotes and some video examples! (https://simkit.co/podcast/)